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Government Institution
“L.T.Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine”
(DI "L.T.Mala NIT NAMSU")

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Department of Arterial Hypertension and Prevention of Its Complications

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Tasks and functions of the department

Tasks:

  • The most important mechanisms of the pathogenesis of arterial hypertension and symptomatic (secondary) arterial hypertensions (with endocrine diseases and in generalized atherosclerosis) in-depth study.
  • Establishment of the basic laws of development and progression arterial hypertension and symptomatic (secondary) arterial hypertensions in patients with various diseases of the internal organs (type 2 diabetes, obesity, gout, coronary heart disease, heart failure).
  • Highly informative methods of early diagnosis and prediction of target-organs lesions in patients with arterial hypertension and symptomatic (secondary) arterial hypertensions development.
  • Pathogenetic-based methods for the treatment of arterial hypertension and symptomatic (secondary) hypertension and their cardiovascular complications development.
  • Development of effective approaches to primary and secondary prevention of arterial hypertension in order to prevent or inhibit of life-threatening complications development and progression.

Functions:

  • Conducting research work in accordance with the tasks of the department.
  • Thematic patients for the implementation of research work organization and selection.
  • Organization and conducting of in-depth examination of thematic patients in accordance with modern requirements and plans of research work.
  • Conducting advisory work in the clinic of the Institute and medical work - in the department of arterial hypertension.
  • Ensuring the study of the most important mechanisms of pathogenesis of hypertension and secondary (symptomatic) arterial hypertension.
  • Organization of regular publications of the results of work in professional publications.
  • Ensuring the presentation of research results at the republican and international scientific congresses, scientific conferences, symposiums and roundtables.
  • Patenting of new and effective methods of diagnostics, prognostication, treatment and prevention of arterial hypertension, symptomatic (secondary) arterial hypertension and their complications.
  • Wide of research results into the practice of Ukrainian health care introduction.
  • Carrying out sanitary-educational work among the population on problems of diagnostics, treatment and prevention of arterial hypertension, symptomatic (secondary) arterial hypertension and their complications.
  • Basic scientific direction Is a study of haemodynamics, neurohumoral, membranous-cellular, immune, metabolic mechanisms of development, methods of early differential diagnostics, treatment and prophylaxis of essential hypertension and symptomatic arterial hypertensions, in that number in combination with pathology of internal organs.

Major results of researches

  • The main structural and haemodynamical regularities of development and progress of arterial hypertension have been established. The role of prostaglandins, opioide and sodium-uretics peptides, endothelin-1, hymase, neuropeptide Y in development of different forms of arterial hypertension was identified.
  • The key role of interleukins 1 and 2, membranous-cellular changes in pathogenesis of arterial hypertensions and its complications were showed.
  • The feature of daily profile of arterial pressure for patients with the different forms of essential hypertension and symptomatic hypertensions was identified.
  • The conformity to natural laws of changes of leptin and insulin-resistance on the stages of development and progression of metabolic syndrome for patients with arterial hypertension and the optimal methods of the combined therapy of these patients were worked out. It was found out role of insulin-like factor of growth-1 and transforming factor of growth in the processes of heart and vessels remodeling at combination of two most widespread pathologies – arterial hypertension and type 2 of diabetes mellitus.
  • The informing algorithms of early and differential diagnostics of symptomatic arterial hypertensions were created.
  • The effective nonmedicamentous (laser, magnet-therapy, quantum haemotherapy) and medicamentous (with the use of new preparations) methods of treatment of arterial hypertension in that number, on a background the concomitant diseases of internal organs were elaborated.
  • System of prophylaxis of arterial hypertension and its complications for patients with different concomitant pathology at the level of domestic medicine departments was developed.
  • The department was one of the initiators of creation in Ukraine the National program of prophylaxis and treatment of arterial hypertension and conducts large work in this direction in the country and in a region.

The employees of department based on results of research works had published over 700 scientific labors, 6 monographs, 18 methodical recommendations were given out, 45 copyright certificates and patents were received, 2 doctorate and 22 candidate's dissertations were defended. More than 70 science published behind the cordon. A manager of department is by the coauthor of recommendations of Ukrainian society of cardiologists on a prophylaxis and treatment of arterial hypertension and recommendations on diagnostics, treatment and prophylaxis of metabolic syndrome and diabetes mellitus. The clinical base of department is branch of hypertension and diseases of kidneys, which heads by a candidate of medical science, high-category doctor М.М.Dunaevskaya.

 

Staff members of the department:

Koval Sergiy

Snihurska Iryna

Starchenko Tatyana

Miloslavsky Dmitry

Penkova Marina

Bozhko Vadim

Mysnychenko Olga

Yushko Kostiantyn

Government Institution
“L.T.Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine”

Telephone:

(057) 370-28-18
(057) 373-90-67

Address:

2 а, Lyubovi Maloy ave., c. Kharkiv, 61039, Ukraine